Pressure-controlled vs Volume Controlled Ventilation on RV Function During OLV

PHASE3CompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

January 31, 2013

Study Completion Date

March 31, 2013

Conditions
Lung Diseases
Interventions
OTHER

The PCV-VCV group

During the PCV period, the inspiratory pressure will be adjusted to deliver a TV of 6 mL/kg (predicted body weight) to the patient's dependent lung. During the VCV period, the patient's dependent lung will be ventilated with a TV of 6 mL/kg (PBW). Whereas FiO2, I: E ratio, PEEP, frequency, Ppk, and a FGF will be maintained as during two-lung ventilation (TLV) and the lumen of the nondependent lung will be left open to air. Dependent lung recruitment maneuvers will be repeated at 30-minute intervals by raising the inspiratory pressure up to 35 cmH2O for 10 seconds.

OTHER

The VCV-PCV group

During the PCV period, the inspiratory pressure will be adjusted to deliver a TV of 6 mL/kg (predicted body weight) to the patient's dependent lung. During the VCV period, the patient's dependent lung will be ventilated with a TV of 6 mL/kg (PBW). Whereas FiO2, I: E ratio, PEEP, frequency, Ppk, and a FGF will be maintained as during two-lung ventilation (TLV) and the lumen of the nondependent lung will be left open to air. Dependent lung recruitment maneuvers will be repeated at 30-minute intervals by raising the inspiratory pressure up to 35 cmH2O for 10 seconds.

Trial Locations (1)

31592

Anesthesiology Department, Khobar

All Listed Sponsors
lead

Imam Abdulrahman Bin Faisal University

OTHER

NCT01763879 - Pressure-controlled vs Volume Controlled Ventilation on RV Function During OLV | Biotech Hunter | Biotech Hunter