A Controlled Clinical Trial of Cathodal Transcranial Direct Current Stimulation in Patients With Refractory Epilepsy

PHASE2CompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

February 29, 2012

Primary Completion Date

December 31, 2012

Study Completion Date

April 30, 2015

Conditions
Refractory Epilepsy
Interventions
DEVICE

Nicolet Endeavor CR: 30min

Transcranial direct current stimulation (tDCS) is a safe, non-invasive method that modulates cortical excitability. In direct current polarization, the cerebral cortex is stimulated through a weak constant electric current in a noninvasive and painless manner. This weak current induces focal changes of cortical excitability increase or decrease depending on the electrode polarity- that last beyond the period of stimulation.

DEVICE

Nicolet Endeavor CR: 60min

Transcranial direct current stimulation (tDCS) is a safe, non-invasive method that modulates cortical excitability. In direct current polarization, the cerebral cortex is stimulated through a weak constant electric current in a noninvasive and painless manner. This weak current induces focal changes of cortical excitability increase or decrease depending on the electrode polarity- that last beyond the period of stimulation.

DEVICE

Nicolet Endeavor CR: 30min for 3 days

Transcranial direct current stimulation (tDCS) is a safe, non-invasive method that modulates cortical excitability. In direct current polarization, the cerebral cortex is stimulated through a weak constant electric current in a noninvasive and painless manner. This weak current induces focal changes of cortical excitability increase or decrease depending on the electrode polarity- that last beyond the period of stimulation.

DEVICE

Nicolet Endeavor CR: 30min for 5 days

Transcranial direct current stimulation (tDCS) is a safe, non-invasive method that modulates cortical excitability. In direct current polarization, the cerebral cortex is stimulated through a weak constant electric current in a noninvasive and painless manner. This weak current induces focal changes of cortical excitability increase or decrease depending on the electrode polarity- that last beyond the period of stimulation.

DEVICE

Nicolet Endeavor CR: Placebo

The same procedures just that in this case the machine produces only a 60 second stimulus at the beginning so the patient can feel the initial electric stimulus.

Trial Locations (1)

14269

Instituto Nacional de Neurología y Neurocirugía, Mexico City

All Listed Sponsors
collaborator

Massachusetts General Hospital

OTHER

collaborator

University Hospital Freiburg

OTHER

collaborator

Spaulding Rehabilitation Hospital

OTHER

lead

El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez

OTHER

NCT01763294 - A Controlled Clinical Trial of Cathodal Transcranial Direct Current Stimulation in Patients With Refractory Epilepsy | Biotech Hunter | Biotech Hunter