36
Participants
Start Date
August 31, 2013
Primary Completion Date
October 13, 2016
Study Completion Date
October 13, 2016
Leuprolide Acetate
All subjects will receive one IM injection (3.75 mg) each month for four months.
Micronized estradiol
All participants will receive micronized estradiol daily for eight weeks. Estradiol will be started at a dose of 4 mg/day and increased progressively up to 10 mg/day.
Progesterone
All subjects will receive micronized progesterone daily for eight weeks. Progesterone will be started at 400 mg/day and increased progressively up to 800 mg/day.
University of North Carolina at Chapel Hill, Chapel Hill
Foundation of Hope, North Carolina
OTHER
North Carolina Translational and Clinical Sciences Institute
OTHER
National Institutes of Health (NIH)
NIH
National Alliance for Research on Schizophrenia and Depression
OTHER
National Institute of Mental Health (NIMH)
NIH
University of North Carolina, Chapel Hill
OTHER