Low Tidal Volume and EVLWI During OLV

PHASE1CompletedINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

January 31, 2013

Study Completion Date

February 28, 2013

Conditions
Lung Diseases
Interventions
PROCEDURE

The VT 4 ml/kg group

the dependent lung will be ventilated with a TV of 4 mL/kg (predicted body weight), respectively, whereas FiO2, I: E ratio, PEEP, frequency, Ppk, and a FGF will be maintained as during two-lung ventilation (TLV) and the lumen of the nondependent lung will be left open to air. Dependent lung recruitment maneuvers will be repeated at 30-minute intervals by raising the inspiratory pressure up to 35 cmH2O for 10 seconds.

PROCEDURE

The VT 6 ml/kg group

the dependent lung will be ventilated with a TV of 6 mL/kg (predicted body weight), respectively, whereas FiO2, I: E ratio, PEEP, frequency, Ppk, and a FGF will be maintained as during two-lung ventilation (TLV) and the lumen of the nondependent lung will be left open to air. Dependent lung recruitment maneuvers will be repeated at 30-minute intervals by raising the inspiratory pressure up to 35 cmH2O for 10 seconds.

PROCEDURE

The VT 8 ml/kg group

the dependent lung will be ventilated with a TV of 8 mL/kg (predicted body weight), respectively, whereas FiO2, I: E ratio, PEEP, frequency, Ppk, and a FGF will be maintained as during two-lung ventilation (TLV) and the lumen of the nondependent lung will be left open to air. Dependent lung recruitment maneuvers will be repeated at 30-minute intervals by raising the inspiratory pressure up to 35 cmH2O for 10 seconds.

Trial Locations (1)

31592

Anesthesiology Department, Khobar

All Listed Sponsors
lead

Imam Abdulrahman Bin Faisal University

OTHER

NCT01762709 - Low Tidal Volume and EVLWI During OLV | Biotech Hunter | Biotech Hunter