The Underlying Mechanism of Spinal Manipulative Therapy and the Effect of Pain on Physical Outcome Measures

NACompletedINTERVENTIONAL
Enrollment

103

Participants

Timeline

Start Date

January 31, 2013

Primary Completion Date

October 31, 2014

Study Completion Date

October 31, 2014

Conditions
Low Back PainDegeneration of Lumbosacral Intervertebral DiscMuscle WeaknessSpine Stiffness
Interventions
OTHER

SMT for low back pain patients

High velocity, low amplitude spinal manipulative therapy (HVLA-SMT) will be provided to the lumbopelvic region on both sides.

OTHER

Pain induction (optional)

A randomized crossover design is used to investigate the changes in spinal stiffness and back muscle activity of asymptomatic participants following an experimental pain induction procedure. Specifically, asymptomatic participants attend two separate sessions 5 days apart. Participants will receive 0.3 ml of 5% hypertonic saline or 0.9% isotonic saline in random order into the interspinous ligaments at L3 to L5 levels. The resulting temporal changes in pain intensity, spinal stiffness and trunk muscle activity following saline injections will be monitored. During the second session, the participants will undergo the same procedures but with the previously unused saline concentration.

OTHER

Low back pain participants without SMT

No treatment

Trial Locations (1)

T6G 2C8

River Valley Health Clinic, Edmonton

All Listed Sponsors
lead

University of Alberta

OTHER

NCT01761838 - The Underlying Mechanism of Spinal Manipulative Therapy and the Effect of Pain on Physical Outcome Measures | Biotech Hunter | Biotech Hunter