Comparison of Changes of Inflammatory Proteins in Aqueous Humour of Subjects Treated With Avastin vs Lucentis

CompletedOBSERVATIONAL
Enrollment

30

Participants

Timeline

Start Date

July 31, 2012

Primary Completion Date

October 31, 2013

Study Completion Date

September 30, 2014

Conditions
Proliferative Diabetic Retinopathy (PDR)
Interventions
OTHER

Injection of Avastin / Lucentis, sampling aqueous humour

"Study participants will be divided into two arms. Subjects will receive Avastin or Lucentis a few days before vitrectomy surgery. The assignment will be double-masked.The first sample of aqueous humor will be obtained immediately prior to the intravitreal injection.~On the same of the intravitreal injection, a blood sample will be taken for hemoglobin A1C measurement. Approximately 1 week later when patients are having their scheduled vitrectomy surgery, an additional sample of aqueous humour will be obtained .~Intraocular cytokines levels will be measured in aqueous humor samples using multiplex cytokine assays."

Trial Locations (1)

V5Z3N9

UBC/VGH Eye Care Centre, Vancouver

All Listed Sponsors
lead

University of British Columbia

OTHER

NCT01760746 - Comparison of Changes of Inflammatory Proteins in Aqueous Humour of Subjects Treated With Avastin vs Lucentis | Biotech Hunter | Biotech Hunter