Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung

PHASE2TerminatedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

April 30, 2013

Primary Completion Date

January 31, 2017

Study Completion Date

May 31, 2017

Conditions
OsteosarcomaMetastatic Osteosarcoma
Interventions
DRUG

pazopanib

"For subjects \> 18 years of age and subjects 16-17 years of age with a BSA ≥ 1.6 Pazopanib 800mg once daily will be started on Cycle 1 Day 1 and will be administered continuously for each 28-day cycle. Subjects may continue study treatment until they develop disease progression or unacceptable toxicity.~For subjects 16-17 years of age with a BSA \< 1.6 m2, Pazopanib 600mg once daily will be started on Cycle 1 Day 1 and will be administered continuously for each 28-day cycle. Subjects may continue study treatment until they develop disease progression or unacceptable toxicity."

Trial Locations (4)

55905

Mayo Clinic, Rochester

77030

MD Anderson Cancer Center, Houston

91010

City of Hope, Duarte

02114

Massachusetts General Hospital/Dana Farber Cancer Institute, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis

INDUSTRY

lead

Emerald Clinical Inc.

INDUSTRY

NCT01759303 - Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung | Biotech Hunter | Biotech Hunter