Safety Study of HLA-haplo Matched Allogenic Bone Marrow Derived Stem Cell Treatment in Amyotrophic Lateral Sclerosis

PHASE1CompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

December 31, 2012

Primary Completion Date

April 10, 2017

Study Completion Date

April 10, 2017

Conditions
Amyotrophic Lateral SclerosisMotor Neuron DiseaseNeuromuscular DiseaseNeurodegenerative DiseaseCentral Nervous System Disease
Interventions
GENETIC

HYNR-CS-Allo

The patients enrolled in the trial will be successively allocated into three cohorts for HYNR-CS-Allo inj., 0.25 X 10\^6 cells/kg, 0.5 X 10\^6 cells/kg, 1 X 10\^6 cells/kg, according to the 3+3, up and down protocol design. The first treatment cohort will be 0.5 X 10\^6 cells/kg dose cohort.

Trial Locations (1)

133-792

Hanyang University Seoul Hospital, Cell Therapy Center for Neurologic Disorders, Seoul

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Corestemchemon, Inc.

INDUSTRY

lead

Hanyang University Seoul Hospital

OTHER

NCT01758510 - Safety Study of HLA-haplo Matched Allogenic Bone Marrow Derived Stem Cell Treatment in Amyotrophic Lateral Sclerosis | Biotech Hunter | Biotech Hunter