Factors Responsible for the Effectiveness of the Lund De-airing Technique

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

September 30, 2012

Primary Completion Date

December 31, 2013

Study Completion Date

January 31, 2014

Conditions
Complication of Surgical Procedure
Interventions
PROCEDURE

Open pleurae & conventional filling of heart

After completion of the left heart surgery, the heart will be actively filled with blood from the cardiopulmonary bypass circuit and lungs fully ventilated with positive end-expiratory pressure to flush out all air trapped in the lung veins and left heart. When there is no more visible air seen on Trans-esophageal echocardiography, the patient is weaned from cardiopulmonary bypass.

PROCEDURE

Intact pleurae & staged filling of heart

After the end of the left heart surgery, the heart is gradually filled with blood from the cardiopulmonary bypass circuit. Cardiac contractions fill the lungs with blood til no more air is seen in left heart on Trans-esophageal Echocardiography. Thereafter the lungs are ventilated with 50% of the estimated lung minute volume and 5 cm positive end-expiratory pressure and cardiac filling and de-airing continued. If no air is seen in the left heart full ventilation is started and the patient is weaned from cardiopulmonary bypass.

Trial Locations (1)

22350

Lund University, Lund

All Listed Sponsors
lead

Lund University

OTHER

NCT01757704 - Factors Responsible for the Effectiveness of the Lund De-airing Technique | Biotech Hunter | Biotech Hunter