56
Participants
Start Date
January 7, 2013
Primary Completion Date
December 6, 2016
Study Completion Date
January 1, 2025
Bendamustine
Bendamustine will be administered intravenously over 1 hour (if using Treanda) or over 10 minutes (if using Bendeka) on day 1, every 28 days for 12 cycles.
Pomalidomide
Pomalidomide will be administered once daily orally (PO) on days 1-21, every 28 days until disease progression or death.
Dexamethasone
Dexamethasone will be administered weekly orally or intravenously on days 1, 8, 15, and 22 every 28 days until disease progression or death. After 6 cycles of treatment, the dose may be reduced to 20mg at investigator's discretion. For subjects ≥ 75 years of age, the starting dose of dexamethasone is 20 mg/day on Days 1, 8, 15 and 22 of each 28-day treatment cycle.
Duke University Medical Center, Durham
Collaborators (1)
Celgene
INDUSTRY
Cristina Gasparetto
OTHER