SGI-110 in the Treatment of Advanced Hepatocellular Carcinoma (HCC)

PHASE2CompletedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

December 31, 2012

Primary Completion Date

September 30, 2015

Study Completion Date

September 30, 2015

Conditions
Hepatocellular Carcinoma
Interventions
DRUG

SGI-110

SGI-110 will be administered by subcutaneously (SC) on Days 1 - 5 every 28 days until disease progression or unacceptable toxicity

Trial Locations (24)

10032

Columbia University Medical Center - Herbert Irving Comprehensive Cancer Center, New York

19111

Fox Chase Cancer Center, Philadelphia

29425

Medical University of South Carolina, Hollings Cancer Center, Charleston

33612

H. Lee Moffitt Cancer Center and Research Institute, Tampa

38138

The Jones Clinic, PC, Germantown

40201

University of Louisville James Graham Brown Cancer Center, Louisville

43210

The Ohio State University Comprehensive Cancer Center, Columbus

53792

UW Carbone Cancer Center, Madison

60611

Northwestern University: Robert H. Lurie Comprehensive Cancer Center, Chicago

75230

Mary Crowley Medical Research Center, Dallas

75390

University of Texas Southwestern Medical Center, Dallas

90033

USC Norris Comprehensive Cancer Center, Los Angeles

91010

City of Hope National Medical Center, Duarte

95817

UC Davis Comprehensive Cancer Center, Sacramento

98122

Swedish Cancer Institute, Seattle

V5Z 1M9

University of British Columbia and Vancouver General Hospital, Vancouver

K1H 8L6

The Ottawa Hospital Cancer Center, Ottawa

M4N 3M5

Sunnybrook HealthScience Centre, Toronto

H2X 3J4

CHUM Hopital St-Luc, Montreal

J1N 5N4

Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke

Unknown

University of Liverpool Clatterbridge Cancer Center, Liverpool

EC1V 4AD

Cambridge University Hospitals NHS Foundation Trust, London

W12 0NN

Imperial College Healthcare NHS Foundation Trust, London

WC1E 6BT

University College London, London

Sponsors
All Listed Sponsors
lead

Astex Pharmaceuticals, Inc.

INDUSTRY