NCT01747174View on ClinicalTrials.gov

REperfusion Facilitated by LOcal Adjunctive Therapy in ST-elevation Myocardial Infarction

PHASE2CompletedINTERVENTIONAL
Enrollment

247

Participants

Timeline

Start Date

October 31, 2011

Primary Completion Date

October 31, 2014

Study Completion Date

December 31, 2014

Conditions
ST-elevation Myocardial Infarction (STEMI)
Interventions
DRUG

IC Adenosine

IC Adenosine 1mg injected distally via micro-catheter in to IRA following thrombus aspiration with further dose (1mg if IRA is RCA otherwise 2mg) via guide catheter following coronary stent deployment.

DRUG

IC Sodium nitroprusside (SNP)

IC SNP 250mcg injected distally via micro-catheter distally in to IRA following thrombus aspiration with further 250 mcg dose delivered via guide catheter following coronary stent deployment.

PROCEDURE

Standard PCI

PCI procedure with thrombectomy (via aspiration catheter) and bivalirudin given as standard.

Trial Locations (4)

LE3 9QP

Glenfield Hospital, Leicester

NE7 7DN

Freeman Hospital, Newcastle upon Tyne

CV2 2DX

University Hospital, Coventry

LS1 3EX

Leeds General Infirmary, Leeds

All Listed Sponsors
lead

University Hospitals, Leicester

OTHER

NCT01747174 - REperfusion Facilitated by LOcal Adjunctive Therapy in ST-elevation Myocardial Infarction | Biotech Hunter | Biotech Hunter