Azacitidine and Lenalidomide for Relapsed and Refractory Patients With Acute Myeloid Leukemia

PHASE2CompletedINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

December 6, 2012

Primary Completion Date

April 27, 2016

Study Completion Date

August 3, 2016

Conditions
Acute Myeloid Leukemia
Interventions
DRUG

Azacitidine

Enrolled patients will receive 75 mg/m2 of azacitidine subcutaneously (SC) or intravenously (IV) on days 1-7 alone.

DRUG

Lenalidomide

Beginning on day 8, patients will receive 50 mg of lenalidomide PO, and will take this daily from day 8 through 28.

OTHER

Off Therapy

2 weeks off therapy, then begin sequence again for 12 weeks.

Trial Locations (1)

80045

University of Colorado Cancer Center, Aurora

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Celgene

INDUSTRY

lead

University of Colorado, Denver

OTHER