Dose-Escalation Trial of Carfilzomib With and Without Romidepsin in Cutaneous T-Cell Lymphoma

PHASE1TerminatedINTERVENTIONAL
Enrollment

7

Participants

Timeline

Start Date

March 22, 2013

Primary Completion Date

October 11, 2016

Study Completion Date

October 11, 2016

Conditions
Recurrent Cutaneous T-cell Non-Hodgkin LymphomaRecurrent Mycosis Fungoides/Sezary SyndromeStage I Cutaneous T-cell Non-Hodgkin LymphomaStage IA Mycosis Fungoides/Sezary SyndromeStage IB Mycosis Fungoides/Sezary SyndromeStage II Cutaneous T-cell Non-Hodgkin LymphomaStage IIA Mycosis Fungoides/Sezary SyndromeStage IIB Mycosis Fungoides/Sezary SyndromeStage III Cutaneous T-cell Non-Hodgkin LymphomaStage IIIA Mycosis Fungoides/Sezary SyndromeStage IIIB Mycosis Fungoides/Sezary SyndromeStage IV Cutaneous T-cell Non-Hodgkin LymphomaStage IVA Mycosis Fungoides/Sezary SyndromeStage IVB Mycosis Fungoides/Sezary Syndrome
Interventions
DRUG

carfilzomib

Given IV

DRUG

romidepsin

Given IV

OTHER

laboratory biomarker analysis

Correlative studies

Trial Locations (1)

60611

Northwestern University, Chicago

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Amgen

INDUSTRY

lead

Northwestern University

OTHER

NCT01738594 - Dose-Escalation Trial of Carfilzomib With and Without Romidepsin in Cutaneous T-Cell Lymphoma | Biotech Hunter | Biotech Hunter