rhTPO Combining Dexamethasone Versus High-dose Dexamethasone for Initial Treatment of ITP

PHASE3CompletedINTERVENTIONAL
Enrollment

158

Participants

Timeline

Start Date

July 31, 2012

Primary Completion Date

July 31, 2014

Study Completion Date

November 30, 2014

Conditions
PurpuraIdiopathic Thrombocytopenic Purpura
Interventions
DRUG

recombinant human thrombopoietin (rhTPO); dexamethasone

Patients in recombination treatment group take rhTPO( subcutaneously , 300U/kg for 14 consecutive days, followed by flexible treating dosage so as to keep the platelet count above 50×10\^9/L until the 28th day), in combination with dexamethasone(intravenously , 40mg/d for 4 consecutive days)

DRUG

Dexamethasone

Patients in single treatment group take dexamethasone intravenously at 40 mg daily for 4 consecutive days.

Trial Locations (1)

Unknown

Qilu Hospital, Shandong University, Jinan

All Listed Sponsors
collaborator

The Affiliated Hospital of the Chinese Academy of Military Medical Sciences

OTHER

collaborator

Anhui Medical University

OTHER

collaborator

The First Affiliated Hospital of Dalian Medical University

OTHER

collaborator

Shandong Provincial Hospital

OTHER_GOV

collaborator

Shenzhen Second People's Hospital

OTHER

collaborator

China Medical University, China

OTHER

collaborator

Zhejiang Provincial Hospital of TCM

OTHER

lead

Shandong University

OTHER

NCT01734044 - rhTPO Combining Dexamethasone Versus High-dose Dexamethasone for Initial Treatment of ITP | Biotech Hunter | Biotech Hunter