Recombinant Human Endostatin Continued Pumping Into Vein Combining With CCRT in Unresectable Stage III NSCLC

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

73

Participants

Timeline

Start Date

November 30, 2012

Primary Completion Date

June 30, 2015

Study Completion Date

June 30, 2015

Conditions
Stage III Non-small-Cell Lung Cancer
Interventions
DRUG

Recombinant human endostatin

Recombinant human endostatin(7.5mg/m2/24h) Continued Pumping Into Vein through 5 days at week 1, 3, 5, and 7,combined with concurrent chemo-radiotherapy.

DRUG

Etoposide (50mg/m2) IV (in the vein) on day 1 to day 5 of a 28-day cycle for 2 cycles

DRUG

cisplatinum (50mg/m2) IV (in the vein) on day 1 and day 8 of a 28-day cycle for 2 cycles

OTHER

laboratory biomarker analysis

OTHER

CT perfusion imaging

Trial Locations (1)

310022

Zhejiang Cancer Hospital, Hangzhou

All Listed Sponsors
collaborator

Chinese Academy of Medical Sciences

OTHER

collaborator

Fudan University

OTHER

collaborator

Peking University Cancer Hospital & Institute

OTHER

collaborator

Tianjin Medical University Cancer Institute and Hospital

OTHER

collaborator

Shandong Cancer Hospital and Institute

OTHER

collaborator

Jiangsu Cancer Institute & Hospital

OTHER

collaborator

Fujian Cancer Hospital

OTHER_GOV

collaborator

The First People's Hospital of Lianyungang

OTHER

lead

Zhejiang Cancer Hospital

OTHER

NCT01733589 - Recombinant Human Endostatin Continued Pumping Into Vein Combining With CCRT in Unresectable Stage III NSCLC | Biotech Hunter | Biotech Hunter