Icotinib or Whole Brain Irradiation in EGFR-mutant Lung Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

176

Participants

Timeline

Start Date

October 14, 2012

Primary Completion Date

June 30, 2015

Study Completion Date

September 14, 2016

Conditions
Brain MetastasisNon Small Cell Lung Cancer
Interventions
RADIATION

whole brain radiation(WBI)

WBI (30Gy/3Gy/10 fractions) plus concurrent or sequential chemotherapy for 4-6 cycles

DRUG

Icotinib

administered orally at a dose of 125 mg 3 times daily

Trial Locations (2)

510080

Guangdong General Hospital, Guangzhou

Guangdong Lung Cancer Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou

All Listed Sponsors
collaborator

Guangdong Provincial People's Hospital

OTHER

lead

Guangdong Association of Clinical Trials

OTHER

NCT01724801 - Icotinib or Whole Brain Irradiation in EGFR-mutant Lung Cancer | Biotech Hunter | Biotech Hunter