A Study To Assess The Safety Of PF-05335810 In Hypercholesterolemic Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

133

Participants

Timeline

Start Date

July 31, 2012

Primary Completion Date

October 31, 2013

Study Completion Date

October 31, 2013

Conditions
Hypercholesterolemia
Interventions
BIOLOGICAL

PF-05335810 Dose A

Single SC Injection

BIOLOGICAL

PF-05335810 Dose B

Single Subcutaneous Injection(s)

BIOLOGICAL

Placebo

Single Subcutaneous Injection(s)

BIOLOGICAL

PF-05335810 Dose B

Single Intravenous Infusion

BIOLOGICAL

Placebo

Single Intravenous Infusion

BIOLOGICAL

PF-04950615 Dose A

Single Subcutaneous Injection(s)

BIOLOGICAL

PF-04950615 Dose A

Single Intravenous Infusion

BIOLOGICAL

PF-05335810 Dose C

Single Subcutaneous Injection(s)

BIOLOGICAL

Placebo

Single Subcutaneous Injection(s)

BIOLOGICAL

PF-05335810 Dose C

Single Intravenous Infusion

BIOLOGICAL

Placebo

Single Intravenous Infusion

BIOLOGICAL

PF-04950615

Single Subcutaneous Injection(s)

BIOLOGICAL

PF-05335810 Dose D

Single Subcutaneous Injection(s)

BIOLOGICAL

Placebo

Single Subcutaneous Injection(s)

BIOLOGICAL

PF-05335810 Dose E

Multiple fixed dosages administered in subcutaneous injections, monthly for 3 months.

BIOLOGICAL

PF-05335810 Dose D

Single Intravenous Infusion

BIOLOGICAL

Placebo

Single Intravenous Infusion

Trial Locations (7)

33143

Pfizer Investigational Site, South Miami

33169

Pfizer Investigational Site, Miami

45227

Pfizer Investigational Site, Cincinnati

49007

Pfizer Investigational Site, Kalamazoo

66212

Pfizer Investigational Site, Overland Park

78209

Pfizer Investigational Site, San Antonio

06511

Pfizer Investigational Site, New Haven

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT01720537 - A Study To Assess The Safety Of PF-05335810 In Hypercholesterolemic Subjects | Biotech Hunter | Biotech Hunter