Hepatocellular Carcinoma Treated With Iodine-125 Implantation

PHASE3CompletedINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

January 31, 2000

Primary Completion Date

August 31, 2012

Study Completion Date

October 31, 2012

Conditions
Liver Carcinoma
Interventions
PROCEDURE

Radiofrequency Ablation

For RFA, we used a commercially available system (RF 2000; Radio Therapeutics, Mountain View, Calif) and a needle electrode with a 15-gauge insulated cannula that had 10 hook-shaped expandable electrode tines with a diameter of 3.5 cm at expansion (LeVeen; Radio Therapeutics).The radioactivity per seed ranged from 0.5 to 0.6 millicuries (mCi)

RADIATION

iodine

The 125I seeds (0.8 mm in diameter and 4.5mm in length) were enclosed in a NiTinol capsule (China Institute of Atomic Energy, Beijing). These seeds could produce 27.4-31.5 keV X-ray and 35.5 Kev γ ray, with a half-life of 59.6 days. The radioactivity per seed ranged from 0.5 to 0.6 millicuries (mCi).

All Listed Sponsors
lead

The Second People's Hospital of GuangDong Province

OTHER

NCT01717729 - Hepatocellular Carcinoma Treated With Iodine-125 Implantation | Biotech Hunter | Biotech Hunter