NCT01708876View on ClinicalTrials.gov

P. Knowlesi Trial of Artesunate-mefloquine Versus Chloroquine

PHASE3CompletedINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

October 31, 2012

Primary Completion Date

December 31, 2014

Study Completion Date

December 31, 2014

Conditions
Uncomplicated Plasmodium Knowlesi Malaria
Interventions
DRUG

Artesunate-mefloquine

DRUG

Chloroquine

DRUG

Primaquine

Given to P. vivax patients only. Delayed administration at day 28; 0.5mg/kg for children or 45mg for adults; normal G6PD activity (once daily administration for 14 days); moderate G6PD deficiency (once weekly for 8 weeks); severe G6PD deficiency (contraindicated / not given).

Trial Locations (3)

89057

Kudat District Hospital, Kudat

89108

Kota Marudu District Hospital, Kota Marudu

Unknown

Pitas District Hospital, Pitas

All Listed Sponsors
collaborator

Ministry of Health, Malaysia

OTHER_GOV

lead

Menzies School of Health Research

OTHER

NCT01708876 - P. Knowlesi Trial of Artesunate-mefloquine Versus Chloroquine | Biotech Hunter | Biotech Hunter