Bendamustine, Lenalidomide (Revlimid®) and Dexamethasone (BRd) as 2nd-line Therapy for Patients With Relapsed or Refractory Multiple Myeloma

PHASE2CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

March 31, 2012

Primary Completion Date

February 29, 2016

Study Completion Date

February 29, 2016

Conditions
Multiple Myeloma
Interventions
DRUG

Bendamustine

"Induction treatment phase (cycle 1-6):~* Bendamustine 75 mg/m2 i.v day 1 and 2~* Lenalidomide 25 mg p.o. day 1-21~* Dexamethasone 40/20 mg p.o., day 1, 8, 15, 22~* Pegfilgrastim 6 mg s.c., day 3 in case of severe neutropenia~Maintenance treatment phase (cycles 7-18):~* Lenalidomide 25 mg p.o. day 1-21~* Dexamethasone 40/20 mg p.o., day 1, 8, 15, 22"

Trial Locations (1)

9000

Kantonsspital St. Gallen, Sankt Gallen

Sponsors

Collaborators (2)

All Listed Sponsors
collaborator

Celgene Corporation

INDUSTRY

collaborator

Mundipharma Research GmbH & Co KG

INDUSTRY

collaborator

Mundipharma Medical Company

INDUSTRY

collaborator

Amgen

INDUSTRY

lead

Cantonal Hospital of St. Gallen

OTHER