Early Biomarker With 18F-FDG PET for Treatment Optimization of Anti-EGFR Therapy in Patients With Metastatic Colorectal Cancer.

CompletedOBSERVATIONAL
Enrollment

46

Participants

Timeline

Start Date

January 31, 2012

Primary Completion Date

November 3, 2020

Study Completion Date

November 3, 2020

Conditions
Colorectal Cancer
Interventions
BEHAVIORAL

(Early) Imaging of response with [18F-]-FDG PET-CT and kinase activity profiles

Patients will be treated with cetuximab or panitumumab. Two \[18F-\]-FDG PET-CT will be performed to explore early response. Patients will undergo blood sampling and two skin and tumor biopsies for kinase activity profiles.

Trial Locations (1)

1081 HV

VU University Medical Center, Amsterdam

All Listed Sponsors
collaborator

Radboud University Medical Center

OTHER

collaborator

Jeroen Bosch Ziekenhuis

OTHER

collaborator

Leiden University Medical Center

OTHER

collaborator

NKI-AvL

UNKNOWN

collaborator

Academisch Ziekenhuis Groningen

OTHER

lead

Amsterdam UMC, location VUmc

OTHER

NCT01691391 - Early Biomarker With 18F-FDG PET for Treatment Optimization of Anti-EGFR Therapy in Patients With Metastatic Colorectal Cancer. | Biotech Hunter | Biotech Hunter