Efficacy and Safety Study With Diltiazem Hydrochloride Cream to Treat Anal Fissures

PHASE3CompletedINTERVENTIONAL
Enrollment

434

Participants

Timeline

Start Date

October 31, 2012

Primary Completion Date

December 31, 2013

Study Completion Date

January 31, 2014

Conditions
Chronic Anal Fissures
Interventions
DRUG

VEN 307

VEN307 applied three times a day, in and around the anus, for 28 days.

DRUG

Placebo

Placebo cream applied three times a day, in and around the anus, for 28 days.

Trial Locations (103)

10016

HCCA Clinical Research Solutions, New York

10021

Manhattan Surgical Associates, LLP, New York

10022

Colorectal Associates of NY, New York

10075

Medical Research Associates of New York (New York Gastroenterology Associates, LLP), New York

11206

Life Medi-Research and Management, Brooklyn

12601

Premier Medical Group, Poughkeepsie

15146

West Penn Allegheny Health System, Monroeville

17033

Penn State Hershey Medical Center, Hershey

19017

Thomas Jefferson University Hospital, Philadelphia

19102

Drexel Univ College of Medicine, Philadelphia

19111

Temple University Physicians, Jeanes Hospital, Philadelphia

20010

Washington Hospital Center - MedStar Health Research Institute, Washington D.C.

20815

Metropolitan Gastroenterology Group, Chevy Chase Clinical Research, Chevy Chase

21045

Gastro Center of Maryland, Columbia

21201

University of Maryland Medical Center, Baltimore

21401

Investigative Clinical Research, Annapolis

21742

Meritus Center For Clinical Research, Hagerstown

22911

Charlottesville Medical Research, Charlottesville

23320

Gastroenterology Associates of Tidewater, Chesapeake

24016

Jefferson Surgical Clinic, Roanoke

27599

University of North Carolina, Raleigh

27612

Wake Research Associates, Raleigh

27710

Duke University, Durham

28403

Trial Management Associates, Wilmington

28607

Medispect, Boone

29118

Gastroenterology Associates of Orangeburg, PA, Orangeburg

29406

Pain Specialists of Charleston, North Charleston

30024

Atlanta Gastroenterology Consultants, Suwanee

30033

Atlanta Center for Gastroenterology, Decatur

30060

Gastrointestinal Specialist of Georgia, Marietta

30310

Morehouse School of Medicine, Atlanta

30912

Georgia Health Sciences University, Augusta

32127

Advanced Medical Research Center, Port Orange

33021

Private Practice, Hollywood

33024

Private Practice, Pembroke Pines

33135

Advance Medical Research Center, Miami

33140

Akta Medika, Miami Beach

33143

Well Pharma Medical Research Corp., Miami

33160

Innovative Medical Research of South Florida, Aventura

33161

Healthcare Clinical Data, Inc., North Miami

33542

Florida Medical Clinic, P.A., Zephyrhills

33606

University of South Florida, South Campus, Tampa

34102

Gastroenterology Group of Naples, PA, Naples

34711

South Lake Pain Institute, Clermont

36117

Montgomery Women's Health Association, PC, Montgomery

36207

The Crawford Clinic, Anniston

36607

Surgical Association of Mobile, Mobile

36617

University of South Alabama, Mobile

37232

Vanderbilt Univ Dept of Colon and Rectal Surgery, Nashville

38305

HCCA Clinical Research Solutions, Jackson

39202

CRC of Jackson, Jackson

44060

Great Lakes Gastroenterology, Mentor

44106

University Hospitals Case Medical Center, Cleveland

44195

Cleveland Clinic, Cleveland

45415

Dayton Gastroenterology, Inc., Dayton

46202

Indiana University School of Medicine, Indianapolis

46237

Kendrick Regional Medical Center, Indianapolis

48098

Center for Digestive Health, Troy

52242

University of Iowa Hospital and Clinics, Iowa City

53226

Medical College of Wisconsin Department of Surgery, Milwaukee

60004

NCH Medical Group, Arlington Heights

60201

North Shore University Health System, Evanston

64064

Midwest Center for Clinical Research, Lee's Summit

65109

Jefferson City Medical Group, Jefferson City

68114

Colon and Rectal Surgery, Inc, Omaha

70121

Ochsner, New Orleans

71201

Delta Research Partners, Monroe

73104

Institute of Pain Research, Oklahoma City

75010

Research Across America, Dallas

77024

Research Concepts, GP LLC, Houston

77030

University of TX Affiliated Hospitals, Houston

77079

Houston Endoscopy and Research Center, Houston

77586

ColoProctology Associates, Seabrook

80229

Rocky Mountain Clinical Research, LLC, Denver

Rocky Mountain Clinical Research, LLC, Thornton

81008

Colorado Research Works, Pueblo

84132

University of Utah HSC, Salt Lake City

85054

Mayo Clinic - Arizona, Phoenix

85710

Desert Sun Clinical Research, LLC, Tucson

89106

Impact Clinical Trials, Las Vegas

90036

Axis Clinical Trials, Los Angeles

90048

Cedars Sinai, Los Angeles

90067

Gastrointestinal Biosciences, Los Angeles

91356

West Coast Clinical Research, Tarzana

92093

UC San Diego, La Jolla

92324

Arrowhead Regional Medical Center, Colton

92653

Alliance Research Centers, Laguna Hills

92868

University of California - Irvine Medical Center, Orange

94070

Digestive Care Associated, A Medical Corporation, San Carlos

97210

Westover Heights Clinic, Portland

97330

The Corvallis Clinic, Clinical Research Center, Corvallis

97701

Bend Memorial Clinic, Bend

98004

NW Gastroenterology, Bellevue

98101

Digestive Disease Institute, Virginia Mason Medical Center, Seattle

98431

Madigan Army Medical Center, Tacoma

06010

Connecticut Clinical Research Foundation CT Gastroenterology Institute At Bristol Hospital, Bristol

40202-1622

University of Louisville, Louisville

02215

Beth Israel Deaconess Medical Center, Boston

01199

Baystate Medical Center Department of Surgery, Springfield

08360-7072

Gastroenterology Group & Endoscopy Center of South NJ (GGSJ), Vineland

08043-9544

C&R Surgical Assoc of South Jersey, Voorhees Township

28310-7301

Womack Army Medical Center, Fort Bragg

77090-3408

Houston Digestive Disease Clinic, Houston

All Listed Sponsors
lead

Ventrus Biosciences, Inc

INDUSTRY

NCT01690221 - Efficacy and Safety Study With Diltiazem Hydrochloride Cream to Treat Anal Fissures | Biotech Hunter | Biotech Hunter