40
Participants
Start Date
November 30, 2012
Primary Completion Date
May 31, 2016
Study Completion Date
December 31, 2016
Metformini hydrochloridum (Siofor 1000 tbl, Berlin)
"Patients will be randomized into 2 groups (A succession: MET-placebo, B succession: placebo-MET. After 3 months the treatment will be switched.~Titration:~500 mg per day(1/2 tbl 1000 mg once a day - in the morning) after a week increase the dose to 1 tbl á 1000 mg after two weeks increase the dose to 2 x tbl 1000 mg (in the morning and in the evening)"
placebo
Patients will be randomized into 2 groups (A succession: MET-placebo, B succession: placebo-MET. After 3 months the treatment will be switched.
Diabetes Center, Institute of Clinical and Experimental Medicine, Prague
Institute for Clinical and Experimental Medicine
OTHER_GOV