A Study of CNTO 136 (Sirukumab) Administered Subcutaneously in Japanese Patients With Active Rheumatoid Arthritis Unresponsive to Methotrexate or Sulfasalazine

PHASE3CompletedINTERVENTIONAL
Enrollment

122

Participants

Timeline

Start Date

November 30, 2012

Primary Completion Date

March 31, 2015

Study Completion Date

March 31, 2015

Conditions
Arthritis, Rheumatoid
Interventions
DRUG

Sirukumab 100 mg

Sirukumab 100 mg subcutaneous (SC) injection, at Weeks 0, 2, and every 2 weeks through Week 52.

DRUG

Sirukumab 50 mg

Sirukumab 50 mg SC at Weeks 0, 4, and every 4 weeks through Week 52.

DRUG

Placebo

Between sirukumab injections, placebo SC at Weeks 2, 6, and every 4 weeks through Week 52.

Trial Locations (17)

Unknown

Asahikawa

Fukuoka

Hiroshima

Hitachi-Naka

Kagoshima

Kirishima

Kitakyushu

Kobe

Kumamoto

Matsumoto

Miyagi

Ōita

Sapporo

Sendai

Shizuoka

Tokyo

Yokohama

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

GlaxoSmithKline

INDUSTRY

lead

Janssen Pharmaceutical K.K.

INDUSTRY