Evaluation of the Allergenicity of AMPHADASE INJECTION (Hyaluronidase Injection USP)

Subjects received intradermal injections of 0.02 mL Amphadase® (hyaluronidase 150 USP units/mL) at two random sites on their forearms.

Subjects received one intradermal injection of 0.02 mL Histatrol® (histamine base 0.1 mg/mL) at one random sites on their forearms.

Subjects received one intradermal injection of 0.02 mL saline at one random site on their forearm.