Comparison Between Lidocaine, Dexmedetomidine, and Their Combined Infusion in Subjects Undergoing Coronary Artery Bypass Graft

NACompletedINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

September 30, 2012

Primary Completion Date

February 28, 2013

Study Completion Date

February 28, 2013

Conditions
Unstable AnginaCoronary Artery Bypass GraftDexmedetomidineLidocaineMyocardial InjuryArrhythmiaBlood Electrolyte Balance
Interventions
DRUG

Lidocaine infusion

a bolus dose of Lidocaine 1.5 mg/kg after anesthetic induction with following infusion with 2 mg/kg/hr during the surgery and same dose during postoperative 24 hour in ICU.

DRUG

Dexmedetomidine infusion

Dexmedetomidine infusion during anesthetic induction with 0.2 mcg/kg/hr followed by 0.3 \~ 0.7 mcg/kg/hr during the surgery

Trial Locations (1)

135-710

Samsung Medical Center, Seoul

All Listed Sponsors
lead

Samsung Medical Center

OTHER

NCT01688648 - Comparison Between Lidocaine, Dexmedetomidine, and Their Combined Infusion in Subjects Undergoing Coronary Artery Bypass Graft | Biotech Hunter | Biotech Hunter