NCT01688401View on ClinicalTrials.gov

Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).

PHASE1CompletedINTERVENTIONAL
Enrollment

3

Participants

Timeline

Start Date

March 8, 2013

Primary Completion Date

May 31, 2017

Study Completion Date

November 26, 2018

Conditions
Diffuse Intrinsic Pontine Glioma (DIPG)
Interventions
DRUG

Melphalan hydrochloride

"Drug administered intra-arterially (injection in the artery).~Standard dose: Cycle 1: 1 mg, intra-arterial (IA) delivery. Cycle 2: 2 mg, intra-arterial (IA) delivery.~Duration of treatment: Eight weeks total - two cycles of IA chemotherapy, separated by four weeks."

Trial Locations (1)

21287

The Johns Hopkins Hospital, Baltimore

All Listed Sponsors
collaborator

Solving Kids' Cancer

OTHER

lead

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

OTHER

NCT01688401 - Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG). | Biotech Hunter | Biotech Hunter