Investigation on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses of a Long-acting GLP-1 Analogue in Healthy Male Subjects and Male Subjects With Type 2 Diabetes

PHASE1CompletedINTERVENTIONAL
Enrollment

107

Participants

Timeline

Start Date

September 19, 2012

Primary Completion Date

April 8, 2013

Study Completion Date

April 8, 2013

Conditions
DiabetesDiabetes Mellitus, Type 2Healthy
Interventions
DRUG

semaglutide

Start doses of 5 mg and 10 mg with end dose of 20 mg. For oral administration.

DRUG

semaglutide

Start doses of 5 mg and 10 mg with end doses of either 20 mg or 40 mg. For oral administration.

DRUG

semaglutide

Start doses of 5 mg and 10 mg with end doses of either 20 mg, 40 mg or 60 mg. For oral administration.

DRUG

placebo

Placebo semaglutide. For oral administration.

DRUG

placebo

Placebo semaglutide with carrier. For oral administration.

Trial Locations (1)

14050

Novo Nordisk Investigational Site, Berlin

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Novo Nordisk A/S

INDUSTRY

NCT01686945 - Investigation on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses of a Long-acting GLP-1 Analogue in Healthy Male Subjects and Male Subjects With Type 2 Diabetes | Biotech Hunter | Biotech Hunter