An Dose Escalation Trial of Oral BIBF 1120 in Combination With Intravenous Carboplatin and Vinorelbine in Elderly Patients With Advanced Non-Small Cell Lung Cancer - Stage IV (VENUS-2)

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

April 30, 2013

Primary Completion Date

January 31, 2015

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG

BIBF 1120

2 x 150 mg capsules, oral, daily (Start dose)

DRUG

Vinorelbine

25 mg/m2 i.v. on day 1 and 8 (three-week cycle)

DRUG

Carboplatin

AUC 5 i.v. on day 1 (three-week cycle)

Trial Locations (2)

Krankenhaus Großhansdorf, Großhansdorf

Klinikum Kassel GmbH, Kassel