Danhong Injection in the Treatment of Acute Ischemic Stroke

PHASE4CompletedINTERVENTIONAL
Enrollment

1,503

Participants

Timeline

Start Date

March 13, 2013

Primary Completion Date

March 10, 2019

Study Completion Date

March 27, 2019

Conditions
Acute Stroke
Interventions
DRUG

Danhong injection

A kind of injection made from two kind of Chinese herbs: Salvia miltiorrhiza and Safflower. 40ml Danhong injection added into 250ml 0.9% saline by an independent research nurse, sealed with brown bag in order to make the investigators and patients blinded, using brown infusion tube for infusion

PROCEDURE

Standard medical care

Standard medical care is in accordance with China Guideline for the diagnosis and treatment of acute ischemic stroke (2010), including medical care for vital signs, control of temperature, blood pressure and glucose, improving cerebral blood circulation, antiplatelet treatment and nutritional supportive care.

DRUG

placebo

0.9% saline added into 250ml 0.9% saline by an independent research nurse, sealed with brown bag in order to make the investigators and patients blinded, using brown infusion tube for infusion.

Trial Locations (62)

100034

Peking University First Hospital, Beijing

100050

Tiantan Hospital Affiliated to Capital Medical University, Beijing

100053

Xuan Wu Hospital Affiliated to Capital Medical University, Beijing

100088

The Second Artillery General Hospital of Chinese People's Liberation Army, Beijing

110003

People's Liberation Army No.202 Hospital, Shenyang

110016

The General Hospital of Shenyang Military, Shenyang

110046

People's Liberation Army No.463 Hospital, Shenyang

114001

Anshan Central Hospital, Anshan

116001

Affiliated Zhongshan Hospital of Dalian University, Dalian

118015

Dandong First Hospital, Dandong

124013

Panjin Central Hospital, Panjin

130021

Jilin Province People's Hospital, Changchun

The Affiliated Hopital to Changchun University of Chinese Medicine, Changchun

The First Hospital Affiliated to Jilin University, Changchun

130033

China-Japan Union Hospital of Jilin University, Changchun

130041

The Second Hospital of Jilin University, Changchun

136299

Liaoyuan Traditional Chinese Medical Hospital, Liaoyuan

150001

The Second Affiliated Hopital of Harbin Medical University, Harbin

210001

Nanjing Hospital of T.C.M., Nanjing

210003

The Second Affiliated Hospital of Nanjing Medical University, Nanjing

210008

Nanjing Drum Tower Hospital, Nanjing

300193

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin

310005

Xin Hua Hospital of Zhejiang Province, Hangzhou

310006

Zhejiang Provincial Hospital of T.C.M., Hangzhou

310014

Zhejiang Provincial People's Hospital, Hangzhou

313003

Huzhou Central Hospital, Huzhou

400037

Xinqiao Hospital of Third Military Medical University, Chongqing

404000

Chongqing Three Gorges Central Hospital, Chongqing

410004

Changsha Central Hospital, Changsha

410005

The First Hospital of Changsha, Changsha

410007

The second people's hospital of Hunan Province, Changsha

410008

Xiangya Hospital Central-south University, Changsha

430014

The Central Hospital of Wuhan, Wuhan

430030

Zhongnan Hospital of Wuhan University, Wuhan

430033

Zhongshan Hospital of Hubei Province, Wuhan

430050

Fifth Hospital in Wuhan, Wuhan

430060

Renmin Hospital of Wuhan University, Wuhan

430064

Tianyou Hospital Affiliated to Wuhan University of Science & Technology, Wuhan

430399

Huangpi District Hospital of T.C.M., Wuhan

450000

The First Affiliated Hospital of Henan University of T.C.M., Zhengzhou

450003

People's Hospital of Zhengzhou, Zhengzhou

450006

Zhengzhou NO.7 People's Hospital, Zhengzhou

466099

Zhoukou Hospital of T.C.M., Zhoukou

471003

The Second Chinese Medical Hospital of Luoyang City, Luoyang

473007

Nanyang T.C.M. Hospital, Nanyang

473065

Nanshi Hospital of Nanyang, Nanyang

510317

Guangdong No.2 Provincial People's Hospital, Guangzhou

510813

Guangzhou hospital of integrated Chinese and Western medicine, Guangzhou

518028

The Second People's Hospital of Shenzhen, Shenzhen

610072

Teaching Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu

610500

The First Affiliated Hopital of Chengdu Medical College, Chengdu

710003

Shanxi Province Hospital of T.C.M., Xi’an

710054

The PLA Fourth Fifty-one Hospital, Xi’an

710068

Shanxi Provincial People's Hospital, Xi’an

712000

Affiliated Hospital of Shanxi University of Chinese Medicine, Xianyang

The Second Affiliated Hospital of Shanxi University of T.C.M., Xianyang

072750

The Second Central Hospital of Baoding City, Baoding

067000

Affiliated Hospital of Chengde Medical University, Chengde

056001

Handan Central Hospital, Handan

024005

Affiliated Hospital of Chifeng University, Chifeng

032299

Fenyang Hospital of Shanxi Province, Lüliang

030001

The Second Affiliated Hospital to Shanxi Medical University, Taiyuan

All Listed Sponsors
collaborator

China Food and Drug Administration

OTHER_GOV

lead

China Academy of Chinese Medical Sciences

OTHER

NCT01677208 - Danhong Injection in the Treatment of Acute Ischemic Stroke | Biotech Hunter | Biotech Hunter