Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesothelioma

PHASE1CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 3, 2014

Primary Completion Date

September 5, 2018

Study Completion Date

August 19, 2019

Conditions
Malignant Pleural Mesothelioma
Interventions
BIOLOGICAL

Immunotherapy plus chemotherapy

live attenuated double deleted Lm

BIOLOGICAL

Immunotherapy with cyclophosphamide plus chemotherapy

live attenuated double deleted Lm

Trial Locations (5)

19104

University of Pennsylvania Abramson Cancer Center, Philadelphia

20892

National Cancer Institute, Bethesda

33612

H. Lee Moffitt Cancer Center, Tampa

60637

University of Chicago Medical Center, Chicago

94115

University of California at San Francisco, San Francisco

Sponsors
All Listed Sponsors
lead

Aduro Biotech, Inc.

INDUSTRY

NCT01675765 - Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesothelioma | Biotech Hunter | Biotech Hunter