NCT01675362View on ClinicalTrials.gov

Are There Protective Effects of Antioxidants, Calcium Channel Blocker and Angiotensin Receptor Blocker Against Extracorporeal Shockwaves Lithotripsy Induced Renal Injury?

PHASE4CompletedINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

August 31, 2012

Primary Completion Date

August 31, 2014

Study Completion Date

October 31, 2014

Conditions
Kidney Calculi
Interventions
DRUG

Antioxidant group

They will be receive vitamins A, C, E and selenium (Selenium ACE) Dosage: Two tablets before ESWL Then 2 tablets every 8 hours after ESWL for one week

DRUG

Calcium Channel Blockers

They will receive Verapamil (Isoptin 80 mg) Dosage: One tablet 2 hours before ESWL Then one tablet every 12 hours after ESWL for one week

DRUG

Angiotensin receptor blocker group

They will receive Losartan (Cozaar 50 mg) Dosage: One tablet 2 hours before ESWL Then one tablet every day after ESWL for one week

DRUG

Placebo

They will receive placebo

Trial Locations (1)

35516

Urology and Nephrology Center, Al Mansurah

All Listed Sponsors
lead

Mansoura University

OTHER

NCT01675362 - Are There Protective Effects of Antioxidants, Calcium Channel Blocker and Angiotensin Receptor Blocker Against Extracorporeal Shockwaves Lithotripsy Induced Renal Injury? | Biotech Hunter | Biotech Hunter