Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects With Multiple Dupuytren's Contractures

PHASE3CompletedINTERVENTIONAL
Enrollment

715

Participants

Timeline

Start Date

September 30, 2012

Primary Completion Date

July 31, 2013

Study Completion Date

July 31, 2013

Conditions
Dupuytren's Contracture
Interventions
BIOLOGICAL

XIAFLEX / XIAPEX

injection (0.58 mg after reconstitution with sterile diluent \[0.3 mg/mL calcium chloride dihydrate in 0.9% sodium chloride\])

Trial Locations (25)

10021

Hospital for Special Surgery, New York

11733

SUNY Stony Brook, Setauket

16507

Hand Microsurgery & Reconstructive Orthopaedics, Erie

22205

The Arthritis Clinic of Northern Virginia, PA, Arlington

27599

UNC School of Medicine, Chapel Hill

28207

OrthoCarolina Research Institute, Inc., Charlotte

30342

The Hand and Upper Extremity Center, Atlanta

37043

Alpha Clinical Research, LLC, Clarksville

40202

Christine M. Kleinert Institute for Hand and Microsurgery, Inc., Louisville

42503

Lake Cumberland Rheumatology, Somerset

46260

The Indiana Hand to Shoulder Center, Indianapolis

55431

TRIA Orthopedic Center, Minneapolis

59808

Missoula Bone and Joint, Missoula

61107

Rockford Orthopedic Associates, Rockford

66160

University of Kansas Medical Center, Kansas City

73109

Health Research Institute, Oklahoma City

77034

Accurate Clinical Research, Inc., Houston

85018

HOPE Research Institute, Phoenix

85712

Tucson Orthopaedic Institute, Tucson

89128

Nevada Orthopedic and Spine Center, Las Vegas

92024

CORE Orthopaedic Medical Center, Encinitas

92037

Torrey Pines Medical Group, La Jolla

92563

Brigid Freyne, MD, Inc., Murrieta

97701

The Center for Neurosurgical and Orthopedic Care and Research, Bend

07724

Central Jersey Hand Surgery, Eatontown

Sponsors
All Listed Sponsors
lead

Endo Pharmaceuticals

INDUSTRY