Stress Biomarkers:Attaching Biological Meaning to Field Friendly Salivary Measures

PHASE1CompletedINTERVENTIONAL
Enrollment

256

Participants

Timeline

Start Date

October 31, 2012

Primary Completion Date

August 15, 2017

Study Completion Date

August 15, 2017

Conditions
Stress
Interventions
DRUG

Metyrapone

750 mcg, oral, administered twice, 3.5 hours apart

DRUG

Dexamethasone

"Administered twice:~1.5 mg, oral, at 11 pm And 0.25 mg, oral, at bedtime at least one week before or after other administration."

DRUG

Cortrosyn

250 mcg, IV, bolus, in the afternoon.

DRUG

Corticorelin ovine triflutate

100 mcg, IV, over 30 seconds, in the afternoon.

Trial Locations (1)

48109

University of Michigan Health System, Ann Arbor

All Listed Sponsors
lead

University of Michigan

OTHER

NCT01673087 - Stress Biomarkers:Attaching Biological Meaning to Field Friendly Salivary Measures | Biotech Hunter | Biotech Hunter