A Phase 1b Study Assessing GS-7340 in Treatment-Naive Adults With Chronic Hepatitis B

PHASE1CompletedINTERVENTIONAL
Enrollment

51

Participants

Timeline

Start Date

March 31, 2012

Primary Completion Date

April 30, 2013

Study Completion Date

April 30, 2013

Conditions
Chronic Hepatitis B
Interventions
DRUG

GS-7340

Subjects are randomized to receive one of four different doses of GS-7340 over 28 days of therapy.

DRUG

Tenofovir disoproxil fumarate

Subjects will receive 300mg of Tenofovir disoproxil fumarate (TDF) over 28 days of therapy

Trial Locations (19)

1042

Auckland Clinical Studies, Auckland

3004

Alfred Hospital, Melbourne

3084

Austin Health, Melbourne

6009

Linear Clinical Research Ltd, Nedlands

21201

University of Maryland Institute of Human Virology, Baltimore

48202

Henry Ford Health System, Detroit

77030

Baylor College of Medicine - St. Luke's Episcopal Hospital, Houston

92105

Research and Education Inc., San Diego

03168

Monash Medical Centre, Melborne

V6Z2C9

Downtown Infectious Diseases Clinic (University of British Columbia), Vancouver

K1H8L6

The Ottawa Hospital, General Campus, Ottawa

M5G 2C4

Toronto General Hospital, Toronto

H3P3P1

Algorithme Pharma, Montreal

G6W 8H1

Pro-recherche, Saint Romuald

B152TH

University Hospitals Birmingham NHS Foundation Trust, Birmingham

E1 1BB

Grahame Hayton Unit, London

NW1-2BU

University College London Hospital, London

SE5 9RS

Institute of Liver Studies, King's College Hospital, London

NG7 2UH

Nottingham University Hospitals NHS Trust - Queens Medical Centre, Nottingham

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Gilead Sciences

INDUSTRY