52
Participants
Start Date
January 31, 2013
Primary Completion Date
August 31, 2020
Study Completion Date
January 26, 2021
Dexamethasone
"Group 1 Blinded Phase: 8 mg (2 capsules of 4 mg) given orally twice a day for 4 days, then 4 mg given orally twice a day for 3 days.~Open Label Phase Groups 1 and 2: 4 mg by mouth twice a day for 7 days."
Placebo
Group 2 Blinded Phase: Two capsules by mouth twice a day for 4 days, followed by one capsule twice a day for 3 days.
Questionnaires
Questionnaires completed at baseline and at day 7 and 14. It should take about 15 minutes to complete these questionnaires.
Spirometer
Patient to blow into spirometry machine 1 time a day to test lung function.
Phone Calls
Patient called by phone 1 time each day to ask about level of shortness of breath and to remind patient to take capsules. These calls should last about 5 minutes.
University of Texas MD Anderson Cancer Center, Houston
M.D. Anderson Cancer Center
OTHER