Internal Mammary Sentinel Lymph Node Biopsy in Early Breast Cancer Patients With Clinically Axillary Node -Positive

PHASE3CompletedINTERVENTIONAL
Enrollment

126

Participants

Timeline

Start Date

February 28, 2014

Primary Completion Date

September 30, 2017

Study Completion Date

December 31, 2017

Conditions
Breast Cancer
Interventions
PROCEDURE

IM-SLNB

IM-SLNB is performed according to the pre-operative lymphoscintigraphy

RADIATION

99mTc-SC

Two syringes of 0.25\~0.5 mCi 99mTc-SC in 0.2\~1.0 mL volume were injected intraparenchymally into 2 quadrants of breast, at the 6 and 12 o'clock positions.

DEVICE

Histologic Examination

All IMSLNs were analyzed by histologic examination for future therapy planning.

DEVICE

LSG

lymphoscintigraphy was performed 0.5\~1.0 hour before surgery

DRUG

Methylthioninium

Four milliliters of methylthioninium was injected intraparenchymally around the primary tumor 10 min before surgery

Trial Locations (1)

250117

Shandong Cancer Hospital, Jinan

All Listed Sponsors
lead

Shandong Cancer Hospital and Institute

OTHER

NCT01668914 - Internal Mammary Sentinel Lymph Node Biopsy in Early Breast Cancer Patients With Clinically Axillary Node -Positive | Biotech Hunter | Biotech Hunter