Effect of Bile Acids on GLP-1 Secretion

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

November 30, 2012

Primary Completion Date

June 30, 2013

Study Completion Date

June 30, 2013

Conditions
Type 2 DiabetesObesity
Interventions
DRUG

Colesevelam

Colesevelam 3750 mg dissolved in 100 ml saline, administered in a feeding tube at time = 0.

DRUG

Chenodeoxycholic Acid

1.250 mg dissolved in 100 ml saline, administered in a feeding tube at time = 0.

OTHER

saline

100 ml saline

DRUG

Colesevelam 3750 mg + chenodeoxycholic acid 1250 mg

Colesevelam and chenodeoxycholic acid dissolved in 100 ml saline, administered in a duodenal tube at time = 0.

Trial Locations (1)

Unknown

Diabetes Research Division, Department of Internal Medicine, Gentofte Hospital, University of Copenhagen, Hellerup

All Listed Sponsors
lead

University Hospital, Gentofte, Copenhagen

OTHER

NCT01666223 - Effect of Bile Acids on GLP-1 Secretion | Biotech Hunter | Biotech Hunter