High-Dose Deferoxamine in Intracerebral Hemorrhage

PHASE2TerminatedINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

March 18, 2013

Primary Completion Date

January 15, 2014

Study Completion Date

May 10, 2018

Conditions
Intracerebral Hemorrhage
Interventions
DRUG

Deferoxamine

Deferoxamine mesylate(62 mg/kg/day up to a maximum daily dose of 6000 mg/day) given by a continuous IV infusion for 5 consecutive days beginning within 24 hours of ICH symptom onset.

DRUG

Normal saline

This is a placebo. Normal saline will be given by a continuous IV infusion for 5 consecutive days beginning within 24 hours of ICH symptom onset.

Trial Locations (29)

19104

University of Pennsylvania Medical Center, Philadelphia

21201

University of Maryland Medical Center, Baltimore

21287

Johns Hopkins Hospital, Baltimore

22908

University of Virginia Health System, Charlottesville

27514

University of North Carolina Medical Center, Chapel Hill

27705

Duke University Hospital, Durham

29425

Medical University of South Carolina, Charleston

32209

The University of Florida College of Medicine, Jacksonville

43210

The Ohio State University Medical Center, Columbus

44195

The Cleveland Clinic Foundation, Cleveland

48202

Henry Ford Hospital, Detroit

52242

University of Iowa Hospital, Iowa City

77030

The University of Texas Health Science Center, Houston

85013

St. Joseph's Hospital, Phoenix

94110

San Francisco General Hospital, San Francisco

94304

Stanford University Hospital, Palo Alto

97239

Oregon Health & Science University, Portland

98104

Harborview Medical Center, Seattle

06107

Hartford Hospital, Hartford

06510

Yale New Haven Hospital, New Haven

02111

Tufts Medical Center, Boston

02114

Massachusetts General Hospital, Boston

02215

Beth Israel Deaconess Medical Center, Boston

01655

University of Massachusetts Memorial Medical Center, Worcester

02903

Rhode Island Hospital, Providence

T2N 2T9

Foothills Medical Center, Calgary

T6G 2B7

Mackenzie Health Sciences Centre, Edmonton

B3H 3A7

Halifax Infirmary, Halifax

G1J 1Z4

Hôpital de l'Enfant-Jésus - CHU de Québec, Québec

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Medical University of South Carolina

OTHER

collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

collaborator

Massachusetts General Hospital

OTHER

collaborator

Tufts Medical Center

OTHER

collaborator

University of Massachusetts, Worcester

OTHER

collaborator

University of Pennsylvania

OTHER

collaborator

Johns Hopkins University

OTHER

collaborator

University of Maryland

OTHER

collaborator

University of Virginia

OTHER

collaborator

Duke University

OTHER

collaborator

University of North Carolina

OTHER

collaborator

University of Florida

OTHER

collaborator

The Cleveland Clinic

OTHER

collaborator

Henry Ford Hospital

OTHER

collaborator

Ohio State University

OTHER

collaborator

St. Joseph's Hospital and Medical Center, Phoenix

OTHER

collaborator

University of California, San Francisco

OTHER

collaborator

Oregon Health and Science University

OTHER

collaborator

Yale New Haven Hospital

UNKNOWN

collaborator

University of Iowa

OTHER

collaborator

Hartford Hospital

OTHER

collaborator

The University of Texas Health Science Center, Houston

OTHER

collaborator

Rhode Island Hospital

OTHER

collaborator

Stanford University

OTHER

collaborator

University of Washington

OTHER

collaborator

University of Calgary

OTHER

collaborator

Hopital de l'Enfant-Jesus

OTHER

collaborator

University of Alberta

OTHER

collaborator

Dalhousie University

OTHER

lead

Beth Israel Deaconess Medical Center

OTHER