Safety and Immunogenicity of 2 Different Vaccination Schedules of Rabies and Japanese Encephalitis Vaccines in Healthy Adult Subjects

PHASE3CompletedINTERVENTIONAL
Enrollment

661

Participants

Timeline

Start Date

August 31, 2012

Primary Completion Date

December 31, 2012

Study Completion Date

October 31, 2013

Conditions
RabiesJapanese Encephalitis
Interventions
BIOLOGICAL

Rabies

Subjects received three doses of Rabies, whole virus vaccine (inactivated, Germany).

BIOLOGICAL

Japanese Encephalitis

Subjects received two doses of Japanese Encephalitis vaccine.

OTHER

Placebo

Subjects received either two, three, four or five doses of normal saline, 0.9% w/v sodium chloride depending on the vaccine group.

Trial Locations (3)

A-1090

Institute of Specific Prophylaxis and Tropical Medicine Center for Pathophysiology, Infectious Diseases and Immunology Medical University of Vienna, Kinderspitalgasse 15

D-20359

Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74

CH-8006

The University of Zurich, Rämistrasse 71

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Novartis Vaccines

INDUSTRY