1,800
Participants
Start Date
November 21, 2011
Primary Completion Date
May 25, 2015
Study Completion Date
June 24, 2015
Combined Epi-GA/PCEA
An epidural catheter will be placed before the induction of general anesthesia. General anesthesia will be induced and maintained as in the control group, with the addition of epidural anesthesia which will be maintained with the use of 0.375%-0.5% ropivacaine during surgery. Patient-controlled epidural analgesia will be provided after surgery.
GA/PCIA
General anesthesia will be induced with midazolam, propofol, sufentanil and rocuronium. Anesthesia will be maintained with either intravenous (propofol), inhalational (sevoflurane with or without nitrous oxide), or combined intravenous-inhalational anesthetics. Additional opioids (remifentanil, sufentanil, fentanyl, or morphine) and muscle relaxant (rocuronium, atracurium, or cisatracurium) will be administered when deemed necessary by the attending anesthesiologists. Patient-controlled intravenous analgesia will be provided after surgery.
Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital, Beijing
Peking University People's Hospital
OTHER
Peking University Third Hospital
OTHER
Beijing Hospital
OTHER_GOV
Beijing Shijitan Hospital, Capital Medical University
OTHER
Peking University First Hospital
OTHER