NCT01657799View on ClinicalTrials.gov

Comparison of Veliparib and Whole Brain Radiation Therapy (WBRT) Versus Placebo and WBRT in Adults With Brain Metastases From Non-Small Cell Lung Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

307

Participants

Timeline

Start Date

October 19, 2012

Primary Completion Date

January 22, 2015

Study Completion Date

January 22, 2015

Conditions
Brain Metastases From Non-small Cell Lung Cancer
Interventions
DRUG

Veliparib

Veliparib capsules for oral administration

DRUG

Placebo

Placebo to veliparib capsules for oral administration

RADIATION

Whole brain radiation therapy

30.0 grays (Gy) of WBRT given in 10 daily fractions of 3.0 Gy each, excluding weekends and holidays

All Listed Sponsors
lead

AbbVie (prior sponsor, Abbott)

INDUSTRY

NCT01657799 - Comparison of Veliparib and Whole Brain Radiation Therapy (WBRT) Versus Placebo and WBRT in Adults With Brain Metastases From Non-Small Cell Lung Cancer | Biotech Hunter | Biotech Hunter