NCT01656057View on ClinicalTrials.gov

The Impact of Gall Bladder Emptying and Bile Acids on the Human GLP-1-secretion

NACompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

July 31, 2012

Primary Completion Date

October 31, 2013

Study Completion Date

April 30, 2014

Conditions
To Assess the Impact of Bile Acids on Human Glukagon-like-peptide-1 Secretion
Interventions
DRUG

Acetaminophen

Acetaminophen dissolved in 50 ml of water

DRUG

Metformin

Metformin + acetaminophen dissolved in 50 ml of water

DRUG

Colesevelam

Colesevelam + acetaminophen dissolved in 50 ml of water

OTHER

Cholecystokinin-8

iv. infusion of CCK-8, 24 pmol/kg/hour for the first 60 minutes

OTHER

Saline

iv. saline infusion 40 ml/hour for the first 60 minutes

Trial Locations (1)

2900

University Hospital of Copenhagen, Gentofte Hospital, Diabetic Research Division, Copenhagen, Hellerup

All Listed Sponsors
collaborator

University of Copenhagen

OTHER

lead

Filip Krag Knop

OTHER

NCT01656057 - The Impact of Gall Bladder Emptying and Bile Acids on the Human GLP-1-secretion | Biotech Hunter | Biotech Hunter