Beta Blocker Therapy in Moderate to Severe COPD

PHASE4CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

August 31, 2012

Primary Completion Date

July 31, 2016

Study Completion Date

July 31, 2016

Conditions
Chronic Obstructive Pulmonary Disease
Interventions
DRUG

Carvedilol

Dose titration: 3.125mg bid for 1 week, 6.25mg bid for 1 week, 12.5mg bid for 4 weeks.

DRUG

Bisoprolol

Dose titration: 1.25mg od for 1 week, 2.5mg od for 1 week, 5mg for 4 weeks.

DRUG

Beclometasone/formoterol

2 puffs bid for first 5 weeks in each treatment arm

DRUG

Tiotropium

1 puff daily for first 4 weeks of each treatment arm

DRUG

Beclometasone

2 puffs bid for final week (week 6) of each treatment arm

Trial Locations (1)

DD1 9SY

Asthma and Allergy Research Group, Ninewells Hospital and Medical School, University of Dundee, Dundee

All Listed Sponsors
collaborator

Tenovus Scotland

OTHER

lead

University of Dundee

OTHER

NCT01656005 - Beta Blocker Therapy in Moderate to Severe COPD | Biotech Hunter | Biotech Hunter