A Combination of Ipilimumab and Fotemustine for Treat Unresectable Locally Advanced or Metastatic Melanoma

PHASE2CompletedINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

June 30, 2010

Primary Completion Date

May 31, 2012

Study Completion Date

September 30, 2014

Conditions
Metastatic Malignant Melanoma
Interventions
DRUG

Ipilimumab and Fotemustine

Ipilimumab: 10 mg/kg q3 weeks for 4 doses, q12 weeks starting at Week 24 Fotemustine: 100 mg/m2 q1 week for 3 doses, q3 weeks starting at Week 9

Trial Locations (7)

53100

Medical Oncology and Immunotherapy-University Hospital of Siena, Siena

Unknown

National Institute for Cancer Research, Genoa

Immunotherapy and Somatic Cell Therapy Unit, Scientific Institute of Romagna, Meldola

European Institute of Oncology, Milan

Melanoma Unit, San Raffaele Hospital, Milan

Surgical Oncology, National Cancer Institute, Milan

Medical Oncology and Innovative Therapy, National Cancer Institute, Naples

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

Italian Network for Tumor Biotherapy

OTHER