30
Participants
Start Date
June 11, 2013
Primary Completion Date
August 7, 2017
Study Completion Date
August 7, 2017
Leukapheresis
Blood drawn through a needle in a vein in one arm, then passed though a machine to collect white blood cells, and then remaining blood returned back to patient through a needle in a vein in other arm. Procedure will take about 3 hours to complete.
Fludarabine
25 mg/m2 by vein on Days -5 to Day -3.
Cyclophosphamide
250 mg/kg by vein on Days -5 to -3.
T-cell Infusion
Beginning dose of genetically modified cells is \> 5x10\^7/m2 but less than or equal to 5 x10\^8/m2 infused on Day 0.
University of Texas MD Anderson Cancer Center, Houston
M.D. Anderson Cancer Center
OTHER