Weighted Versus Uniform Dose of Tranexamic Acid in Patients Undergoing Primary, Knee Arthroplasty

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

May 31, 2012

Primary Completion Date

March 31, 2015

Study Completion Date

March 31, 2015

Conditions
OsteoarthritisIntraoperative Bleeding
Interventions
DRUG

Tranexamic Acid standard dose

Uniform 1 gram dosing

DRUG

Females Tranexamic Acid weighted dose

Weighted dose--20mg/kg of the drug will be given

DRUG

Females receiving a uniform dose of TA

Patients will receive a uniform 1 gm dose of tranexamic acid prior to tourniquet release during a primary TKA.

DRUG

Males Weighted Dose TA

Weighted dose--20mg/kg of the drug will be given

Trial Locations (1)

60612

Rush University Medical Center, Chicago

All Listed Sponsors
lead

Rush University Medical Center

OTHER

NCT01651806 - Weighted Versus Uniform Dose of Tranexamic Acid in Patients Undergoing Primary, Knee Arthroplasty | Biotech Hunter | Biotech Hunter