Phase 1 Study of Anti-OX40 in Patients With Advanced Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

November 30, 2003

Primary Completion Date

May 31, 2009

Study Completion Date

April 30, 2017

Conditions
Advanced Cancer
Interventions
DRUG

Cohort 1 anti-OX40

0.1 mg/kg anti-OX40 on days 1, 3, and 5

DRUG

Cohort 2 anti-OX40

.4 mg/kg anti-OX40 on days 1, 3, and 5

DRUG

Cohort 3 anti-OX40

2.0 mg/kg anti-OX40 on days 1, 3, and 5

BIOLOGICAL

Tetanus Day 29

Tetanus toxoid vaccine 0.5ml (5 LF/ml tetanus toxoid)on Day 29

BIOLOGICAL

Tetanus Day 1

Tetanus toxoid vaccine 0.5ml (5 LF/ml tetanus toxoid)on Day 1.

BIOLOGICAL

KLH Day 1

1 mg KLH in 1 cc diluent subcutaneously on Day 1.

BIOLOGICAL

KLH Day 29

1 mg KLC in 1 cc diluent by subcutaneous injection on Day 29.

Trial Locations (1)

97213

Providence Cancer Center, Portland

All Listed Sponsors
lead

Providence Health & Services

OTHER

NCT01644968 - Phase 1 Study of Anti-OX40 in Patients With Advanced Cancer | Biotech Hunter | Biotech Hunter