Hypofractionated Proton Beam Radiotherapy for Hepatocellular Carcinoma

NACompletedINTERVENTIONAL
Enrollment

112

Participants

Timeline

Start Date

June 7, 2012

Primary Completion Date

April 30, 2017

Study Completion Date

April 30, 2017

Conditions
Hepatocellular Carcinoma
Interventions
RADIATION

Proton Beam Therapy

"\- Prescription dose to PTV as according to the following dose escalation schema: Arml 1: 60 GyE /10 fx, 6GyE fraction dose, 5 days/week, for HCC free from the alimentary tract (i.e., stomach, duodenum, esophagus, small and large bowel) (more than 2cm from clinical target volume), TLV30 \<40%, and/or RLV30 \<30%) Arm 2: 50 GyE /10 fx, 5GyE fraction dose, 5 days/week, for HCC close to the alimentary tract (less than 2cm from clinical target volume) but not contact with the alimentary tract, TLV30\<50% and RLV30\<40% Arm 3: 35 GyE /10 fx, 4GyE fraction dose, 5 days/week, for HCC contact to the alimentary tract (contact with clinical target volume), TLV30\<60%, and/or RLV30\<50%~\- Dose prescription : 95% isodose volume of prescribed dose encompassed PTV"

Trial Locations (1)

411-769

National Cancer Center, Korea, Goyang-si

All Listed Sponsors
lead

National Cancer Center, Korea

OTHER_GOV

NCT01643824 - Hypofractionated Proton Beam Radiotherapy for Hepatocellular Carcinoma | Biotech Hunter | Biotech Hunter